Restless Legs Syndrome

Overview

RLS causes an irresistible urge to move the legs at rest, driven by dopamine and iron‑metabolism pathways. Symptoms peak at night and fragment sleep.

Health Consequences

Large cohort studies show RLS is associated with higher prevalence of hypertension and a greater incidence of cardiovascular events.

Rebis Treatment Approach

  • Serum ferritin check and iron repletion

  • Magnesium, L‑theanine, or glycine supplementation

  • Low‑dose dopamine agonists when necessary

  • Lifestyle coaching for evening movement and circadian alignment

Connection to Other Health Domains

System Untreated Impact Key Evidence
Cardiovascular &
Metabolic		 Higher rates of hypertension & metabolic syndrome Nurses’ Health Study
Hormone Imbalances Dopamine imbalance alters prolactin & cortisol rhythms Neurology reviews
Immune / Chronic Pain Common in fibromyalgia & small-fiber neuropathy Pain journal 2022
Gastrointestinal IBS patients show ≈30% RLS prevalence (bidirectional) J Neurogastroenterol Motil 2011

Benefits of Treatment

Relieving leg discomfort restores deep‑sleep stages, easing morning fatigue and lowering night‑time blood‑pressure surges.


Key References:

  1. RLS and hypertension in middle‑aged women – https://pmc.ncbi.nlm.nih.gov/articles/PMC3221559/

  2. RLS prevalence in IBS patients – https://pmc.ncbi.nlm.nih.gov/articles/PMC3479257/