
Research Institute
The Rebis Research Institute is our outcomes‑research and data‑analytics arm. We capture real‑world results across all Rebis programs, design prospective studies, and publish peer‑reviewed evidence showing how integrative, airway‑focused sleep care improves health and lowers costs.
Areas of focus
Clinical effectiveness of multidisciplinary sleep interventions
Health‑economics: cost‑effectiveness and return‑on‑investment analyses
Functional‑medicine outcomes & biomarker discovery
Airway dentistry impact on cardiometabolic risk
Digital and remote monitoring technologies
Pediatric sleep health and long‑term development
Conditions we treat
Obstructive sleep apnea
Insomnia
Pediatric sleep disorders
Chronic fatigue
Cardiometabolic and neurocognitive conditions linked to sleep loss
Our approach
Prospective patient registries & pragmatic trials with IRB oversight
Practice‑based research network and academic partnerships
Advanced analytics & AI to mine EHR and wearable data
Transparent reporting—preprints, peer‑reviewed journals, and open‑data summaries
Continuous feedback loops to clinicians for rapid quality improvement
Who benefits
Patients receive care informed by the latest evidence; payers and employers gain proof of lower costs; health systems and policymakers get validated models for value‑based sleep care.
How it improves sleep & health
By turning real‑world data into actionable insights, we accelerate adoption of therapies that shorten diagnostic journeys, raise adherence, and cut per‑patient costs—ultimately improving population health while bending the cost curve.
Key Research
Functional Medicine Model of Care & HRQoL improvements (JAMA Netw Open 2019) – https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2753520
Cleveland Clinic functional medicine cohort shows better outcomes & lower costs (2020) – https://www.ifm.org/news/cleveland-clinic-functional-medicine-improves-outcomes
Health‑resource utilization & cost impact of Integrative Medicine users (2024) – https://www.liebertpub.com/doi/10.1089/jicm.2024.0093
Impact of multidisciplinary sleep apnea group clinic on PAP adherence & feasibility‑cost (2025) – https://pmc.ncbi.nlm.nih.gov/articles/PMC11971166/
CHEST: Multidisciplinary pathway delivers cost‑effective surgical care for OSA (2024) – https://journal.chestnet.org/article/S0012-3692%2824%2904494-5/fulltext